So many ways depending of so many settings
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If you plan to visit entire France, the car is the best way. You can drive and stop whenever and wherever you want. Week ends of July and August are a nightmare on french roads though. And gas is very very expensive
Train offers a wide range of possibilities, especially when you take the TGV ( high speed train ) for long trips. Paris is 3 hours from Marseille. You can walk and enjoy your trip. Stations are well organized, with regular buses and taxis in big cities. However when there is a strike ( 22 may 2008 for example) they are a lot of cancelling and delays.
Bus is very very tiring as it does not stop often and you can't walk in it.
You'd better draw your trip and consult SNCF website as seles told you to manage and verify the connectivity between your way of transport.
A bientôt!Bulle 19 Mag 2008, 04:02 - Denuncia